. Xi-Qi Zhu Full Text Available Neurobiological and neuroimaging studies have emphasized the structural and functional alterations in the striatum of cirrhotic patients, but alterations in the functional connections between the striatum and other brain regions have not yet been explored. Of note, manganese accumulation in the nervous system, frequently reflected by hyperintensity at the bilateral globus pallidus (GP on T1-weighted imaging, has been considered a factor affecting the striatal and cortical functions in hepatic decompensation. We employed resting-state functional magnetic resonance imaging to analyze the temporal correlation between the striatum and the remaining brain regions using seed-based correlation analyses. The two-sample t-test was conducted to detect the differences in corticostriatal connectivity between 44 cirrhotic patients with hyperintensity at the bilateral GP and 20 healthy controls.

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Peiris, David; Phipps-Taylor, Madeleine C.; Stachowski, Courtney A.; Kao, Lee-Sien; Shortell, Stephen M.; Lewis, Valerie A.; Rosenthal, Meredith B.; Colla, Carrie. La guia esta complementada por las actividades de desarrollo del Programa de Energia de Villas de NREL, proyectos pilotos internacionales y programas de. Valery Borzov 'Io, Pietro Mennea e quei superman che sembrano sollevatori' Parla il grande rivale di Pietro Mennea: tra ricordi, commozione e un po' di scetticismo.

Decreased connectivity of the caudate was detected in the anterior/middle cingulate gyrus, and increased connectivity of the caudate was found in the left motor cortex. A reduction in functional connectivity was found between the putamen and several regions, including the anterior cingulate gyrus, right insular lobe, inferior frontal gyrus, left parahippocampal gyrus, and anterior lobe of the right cerebellum; increased connectivity was detected between the putamen and right middle temporal gyrus. There were significant correlations between the corticostriatal connectivity and neuropsychological performances in the patient group, but not between the striatal connectivity and GP signal intensity. These alterations in the corticostriatal functional connectivity suggested the abnormalities in the intrinsic brain functional organiztion among the cirrhotic patients with manganese deposition, and may be associated with development of metabolic encephalopathy. The manganese deposition in nervous system, however, can not be an independent factor predicting the resting. Kolakshyapati, Manish; Adhikari, Rupendra B; Karlowee, Vega; Takayasu, Takeshi; Nosaka, Ryo; Amatya, Vishwa J; Takeshima, Yukio; Akiyama, Yuji; Sugiyama, Kazuhiko; Kurisu, Kaoru; Yamasaki, Fumiyuki 2017-03-31 OBJECTIVE Glioblastoma differentials include intracranial tumors, like malignant lymphomas and metastatic brain tumors with indiscernible radiological characteristics. The purpose of this study was to identify a distinct radiological feature for the preoperative differentiation of glioblastoma from its differentials, which include malignant lymphomas and metastatic brain tumors.

METHODS Preoperative MR images, including diffusion-weighted imaging (DWI) studies (b = 1000 and 4000 sec/mm(2)), obtained in patients with newly diagnosed malignant tumor, were analyzed retrospectively after receiving approval from the institutional review board. Sixty-four patients with histologically confirmed glioblastoma, 32 patients with malignant lymphoma, and 46 patients with brain metastases were included. The presence of a nonenhancing peritumoral DWI high lesion (NePDHL, i.e., hyperintense lesion in a nonenhancing peritumoral area on DWI) was confirmed in both DWI sequences. Gray matter lesions were excluded. Lesions were termed 'definite' if present within 3 cm of the hyperintense tumor border with a signal intensity ratio ≥ 30% when compared with the contralateral normal white matter in both sequences.

Discriminant analysis between the histological diagnosis and the presence of Definite-NePDHL was performed, as well as Kaplan-Meier survival analysis incorporating the existence of Definite-NePDHL. RESULTS In 25% of glioblastoma patients, Definite-NePDHL was present, while it was conspicuously absent in patients with malignant lymphoma and metastatic brain tumors. The specificity and positive predictive value were 100%. In the glioblastoma subset, a higher preoperative Karnofsky Performance Scale score (p = 0.0028), high recursive partitioning analysis class (p = 0.0006), and total surgical removal (p = 0.0012) were associated with better median overall survival. Patients with Definite-NePDHL had significantly early local (p = 0.0467) and distant/dissemination recurrence (p. Ishikawa, Hiroyasu; Meguro, Kenichi; Ishii, Hiroshi; Tanaka, Naofumi; Yamaguchi, Satoshi 2012-05-01 Whether silent infarction can be completely asymptomatic remains unclear.

Although the central cholinergic system affects cognition, little attention has been given to infarction. We hypothesized that specific damage to the cholinergic pathways due to infarction or white matter hyperintensity (WMH) would deteriorate cognition, especially attention.

A total of 502 representative elderly participants enrolled in the Osaki-Tajiri Project in 1998 were studied. Participants with focal neurologic signs or previous history of stroke or transient ischemic attack were excluded from the analysis. MRIs were available for all participants, and the Cholinergic Pathways Hyperintensities scale (CHIPS) was used to assess vascular damage in the cholinergic pathways.

The Mini-Mental State Examination (MMSE), word fluency test, Digit Symbol test, and digit span test were used to assess global cognitive function and several aspects of attention. Participants were divided into 3 groups according to the comorbidity of cerebrovascular disease (CVD) and cholinergic involvement: non-CVD, CVD with cholinergic involvement CVD-Ch(+), and CVD without cholinergic involvement CVD-Ch(-). Cognitive scores were compared among the 3 groups. In the non-CVD group, the correlations between cognitive function and the CHIPS score were examined. The CVD-Ch(+) group exhibited significantly lower scores for the Digit Symbol test compared with the other two groups, regardless of the MMSE score.

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In the non-CVD group, the CHIPS score of white matter changes was irreversibly correlated (ie, biologically meaningful) with the Digit Symbol score in participants age 80 years. Our findings suggest that silent infarction or WMH may deteriorate attention regardless of global cognitive function by interrupting the central cholinergic pathway. Oesterling, R.G.; Marko, S.A.; Tschaeche, A.N. 1991-08-19 Westinghouse Idaho Nuclear Company, Inc. (WINCO) is developing and implementing an information management system, known as Rad IMS, to track and record personnel exposure to ionizing radiation. Rad IMS has been designed to fulfill all the requirements of US Department of Energy (USDOE) Order 5480.11, Radiation Protection for Occupational Workers.' ' This Order requires the contractor to maintain detailed radiation exposure records on all individuals who work at the facility.

These records must be retrievable for the entire working life of the individual and be available to other USDOE contractors on request. To meet these general needs, Rad IMS provides for retrieval of detailed, comprehensive individual exposure histories as well as the usual online interactions to accomplish day-today radiation protection operations.

These two extremes of functionality require different approaches in the WINCO computing environment. The exposure histories include database text, paper, microfilm, and electronic bitmaps. Oesterling, R.G.; Marko, S.A.; Tschaeche, A.N. 1991-08-19 Westinghouse Idaho Nuclear Company, Inc. (WINCO) is developing and implementing an information management system, known as Rad IMS, to track and record personnel exposure to ionizing radiation. Rad IMS has been designed to fulfill all the requirements of US Department of Energy (USDOE) Order 5480.11, ``Radiation Protection for Occupational Workers.`` This Order requires the contractor to maintain detailed radiation exposure records on all individuals who work at the facility. These records must be retrievable for the entire working life of the individual and be available to other USDOE contractors on request.

To meet these general needs, Rad IMS provides for retrieval of detailed, comprehensive individual exposure histories as well as the usual online interactions to accomplish day-today radiation protection operations. These two extremes of functionality require different approaches in the WINCO computing environment. The exposure histories include database text, paper, microfilm, and electronic bitmaps. BA Alassane 2013-07-01 Full Text Available IMS is well integrated with existing voice and data networks, while adopting many of their keycharacteristics.The Call Session Control Functions (CSCFs servers are the key part of the IMS structure.

They are themain components responsible for processing and routing signalling messages.When CSCFs servers (P-CSCF, I-CSCF, S-CSCF are running on the same host, the SIP message can beinternally passed between SIP servers using a single operating system mechanism like a queue. It increasesthe reliability of the network 5, 6. We have proposed in a last work for each type of service (between ICSCFand S-CSCF (call, data, multimedia.23, to use less than two servers well dimensioned andrunning on the same operating system.Instead dimensioning servers, in order to increase performance, we try to model traffic on IMS nodes,particularly on entries nodes; it will provide results on separation of incoming flows, and then offer moresatisfactory service. Moon, Won Jin; Park, Ju Yeon; Yun, Won Sung; Jeon, Ji Yeong; Moon, Yeon Sil; Kim, Hee Jin; Han, Seol Heui Konkuk University School of Medicine, Seoul (Korea, Republic of); Kwak, Ki Chang; Lee, Jong Min Dept. Of Biomedical Engineering, Hanyang University, Seoul (Korea, Republic of) 2016-09-15 Neuromelanin loss of substantia nigra (SN) can be visualized as a T1 signal reduction on T1-weighted high-resolution imaging.

We investigated whether volumetric analysis of T1 hyperintensity for SN could be used to differentiate between Parkinson's disease dementia (PDD), Alzheimer's disease (AD) and age-matched controls. This retrospective study enrolled 10 patients with PDD, 18 patients with AD, and 13 age-matched healthy elderly controls. MR imaging was performed at 3 tesla. To measure the T1 hyperintense area of SN, we obtained an axial thin section high-resolution T1-weighted fast spin echo sequence. The volumes of interest for the T1 hyperintense SN were drawn onto heavily T1-weighted FSE sequences through midbrain level, using the MIPAV software. The measurement differences were tested using the Kruskal-Wallis test followed by a post hoc comparison. A comparison of the three groups showed significant differences in terms of volume of T1 hyperintensity (p For Teens I'm Pregnant.

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